Understanding the Natural History Early in the Course or Presentation of Friedreich Ataxia

Inclusion criteria for participants with FA: 1. Genetic diagnosis of Friedreich Ataxia 2. Ages 4-21 years at enrollment 3. Enrollment in the UNIFAI study and ability to have simultaneous visits for both UNIFAI and EARLY-FA 4. Informed consent must be obtained for all participants: 1. For underage participants, they and the parent/ legally authorized representative have to sign the informed consent form, child assent (if applicable) 2. Persons who are not legally competent require the informed consent of their legally authorized representative Inclusion criteria for control participants: 1. Ages 4-21 years at enrollment 2. Matching criteria to an enrolled participant with FA (age, sex and educational status) 3. Informed consent must be obtained for all participants: 1. For underage participants, they and the parent/ legally authorized representative have to sign the informed consent form, child assent (if applicable) 2. Persons who are not legally competent require the informed consent of their legally authorized representative Exclusion criteria for participants with FA: 1. Diagnosis of non-FA medical or other condition that in the opinion of the investigator would interfere with the conduct and assessments of the study or be confounding and contraindication to participation. 2. Pregnant female participants 3. Unable to provide informed consent. Exclusion criteria for control participants: 1. Family risk for FA with unknown status 2. Diagnosis of a medical condition that in the opinion of the investigator could be confounding and contraindication to participation 3. Unable to provide informed consent