Clinical Characteristics and Surgical Outcomes of Full-thickness Macular Hole Without Focal Vitreomacular Traction.

St. Marianna University School of Medicine100 enrolled

Overview

This multicenter, retrospective, observational comparative study. We occasionally encounter FTMHs in which PVD has not been achieved and VMT is absent. These FTMHs cannot be defined by stage in the Gass1) or IVTS3) classification. It is not known whether traction is involved in the development of these atypical macular holes, but they are often classified as Gass stage 2 or 3 according to the size of the hole. The aim of this study was to investigate the clinical features and surgical outcomes of FTMHs without focal VMT and to discuss possible underlying mechanisms.

The clinical characteristics and surgical outcomes the patients diagnosed with FTMH without focal VMT in the macula (classified as VMT-) are presented, in addition to a comparative analysis of the patients presenting with classic stage 2 FTMH with focal VMT (classified as VMT+) according to international classification criteria.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Macular Holes

Interventions

vitrectimyOTHER

Clinical characteristics and surgical outcomes

Eligibility

Sex: ALLMin age: 19 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- macular hole without posterior vitreous detachment at the fovea Exclusion Criteria: * macular hole with posterior vitreous detachment at the fovea * Stage1.3.4 macular hole * Macular hole-associated retinal detachment * Macular hole with subretinal hemorrhage * Traumatic MH

Outcomes

Primary Outcomes

postoperative visual acuity

logMAR visual acuity

Time frame: 1month, 3, 6 and 12 months

Secondary Outcomes

postoperative status of outer retinal layer in OCT B-scan images

External limiting mambrane, Elipsoid zone, Interdegitaion zone

Time frame: 1month, 3, 6 and 12 months