Evaluation of Respiratory Parameters in Patients With Upper Limb Lymphedema

Istanbul University - Cerrahpasa82 enrolled

Overview

The aim of our study is to assess disease severity, respiratory muscle strength, respiratory functions, pectoralis minor muscle shortening, functionality, and quality of life (QoL) in patients with upper limb lymphedema (ULL), and to compare these findings with healthy controls.The disease severity was assessed using the Stillwell classification system; respiratory muscle strength was measured through maximum inspiratory and expiratory intraoral pressures (MIP, MEP, respectively); respiratory functions were evaluated with a spirometer; pectoralis minor muscle shortening was measured with a tape measure; functionality was assessed using the Disabilities of the Arm, Shoulder and Hand (DASH); and QoL was evaluated with the Lymphedema Quality of Life Questionnaire - Arm (LYMQOL-Arm).

The study had a cross-sectional observational study design. The participants were divided into two groups, patients with ULL in Group 1; the healthy individuals were included in Group 2. All assessments for both groups were performed by two different physiotherapists.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lymphedema of Upper Limb

Interventions

Assessments of respiratory parameters

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * aged 25-65 years with secondary, unilateral upper limb lymphedema in Phase 2 of the protection stage, * wearing compression garments, * who have not received manual lymph drainage (MLD) therapy in the last 3 months * along with healthy controls of a similar age who volunteered to participate. Exclusion Criteria: * being in Phase 1 of lymphedema treatment (the edema-reducing phase), * being classified as NYHA Class III and/or IV according to the New York Heart Association classification system, * having a chronic respiratory disease, * presence of active infection (such as lymphangitis or cellulitis), or undergoing radiotherapy/chemotherapy due to breast cancer.

Outcomes

Primary Outcomes

MIP and MEP value

assessments include maximal inspiratory intraoral pressure (MIP) and expiratory intraoral pressure (MEP).

Time frame: 9 months

FVC

FVC is used for forced vital capacity which measure by spirometer

Time frame: 9 months

pectoralis minor muscle length

pectoralis minor muscle length is used for pectoralis muscle shortness

Time frame: 9 months

DASH questionnaire

Disabilities of the Arm, Shoulder and Hand (DASH) is used for upper extremity functions. Questionnaire score ranged between 0-100. A higher total score indicates decreased functionality.

Time frame: 9 months

LYMQOL-Arm questionnaire

Lymphedema Quality of Life Questionnaire - Arm is used for assess disease related quality of life.The high scores are indicative of poorer QoL. Questionnaire score ranged between 0-100.

Time frame: 9 months

Evaluation of Respiratory Parameters in Patients With Upper Limb Lymphedema

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes