Identification of Neuroprognostic Factors for Out-of-hospital Cardiopulmonary Arrest (MIRA29)

N/AActive Not RecruitingNCT06569134

University Hospital, Brest1,200 enrolled

Overview

From the informatized prehospital care registry, data will be collected anonymously for all patients' requiring cardiopulmonary resuscitation for an out-of-hospital cardiac arrest within the Norther Finistere sanitary region. First step of the model derivation will consist in multivariate analysis to extract the most pertinent variates associated with neurological outcome (evaluated using the CPC Score); Second step will consist in the use of artificial intelligence and machine-learning to derive the most discriminant score.

Study Type

OBSERVATIONAL

Enrollment

1,200

Conditions

Cardiac Arrest Neurologic Dysfunction Cognitive Impairment

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Cardiac arrest requiring cardiopulmonary resuscitation Exclusion Criteria: * Death before cardiopulmonary resuscitation * Pediatric Patients

Locations (2)

Outcomes

Primary Outcomes

Cognitive Outcome

It will be evaluated at the end of the ICU stay using the CPC score; a CPC score equal or below 2 will be considered as a good outcome, while a CPC \> 2 will be considered as a bad outcome

Time frame: From date of randomization until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 24 months

Secondary Outcomes

Death OoH

Death after resuscitation during the prehospital care phase

Time frame: Before hospital arrival

Death ICU

Death within the ICU care

Time frame: During ICU stay

Death at Day 28

Death at Day 28, before or after hospital discharge

Time frame: 28 days after cardiac arrest