Caries Inhibitory Effect of Nano Silver and Tri Calcium Phosphate Varnishes Among Visually Impaired Children

Hadeer Mohammed Abd El wahab60 enrolled

Overview

Assessment of pH,streptococcus mutants count, lactobacillus count and immunoglobulin A among visually impaired children after nano silver varnish application it tri calcium phosphate phosphate varnish application

Sixty children will be randomly divided into three equal treatment groups, composed of 20 children each, according to the type of material used as follows: * Group I: children will receive oral health education and nano silver fluoride varnish. * Group II: children will receive oral health education and tri calcium phosphate varnish. * Group III: children will receive oral health education for all children ,Assessment of pH, streptococcus mutants count, lactobacillus count and immunoglobulin A will be assessed at baseline, one day , 3 months and 6 months after application

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Dental Caries

Interventions

Nano silver fluoride varnish and tri calcium phosphate varnishDRUG

Fluoride varnishes

Eligibility

Sex: ALLMin age: 8 YearsMax age: 12 Years

Medical Language ↔ Plain English

Inclusion Criteria: Visually impaired children Exclusion Criteria: * uncooperative children or children not willing to participate in the study. * Children with systemic diseases * Children with bronchial asthma. * Children who were on antibiotic or medications that might affect oral flora or salivary flow taken within the previous 3 months * History of fluoride treatment in the past 3-4 weeks.

Locations (1)

Faculty of dentistry

Tanta, Tanta City, Egypt

Outcomes

Primary Outcomes

Salivary PH

Salivary power of hydrogen at baseline, one month, 3months and six months after intervention

Time frame: 6 months

Salivary streptococcus mutants count

Count of bacteria at baseline, one day, 3months and six months after intervention

Time frame: 6months

Lactobacillus count

Count of bacteria at baseline, one day, 3months and six months after intervention

Time frame: 6 months

Immunoglobulin A

Level of immunoglobulin A at saliva at baseline, one day, 3months and 6 months after intervention

Time frame: 6months

Data from ClinicalTrials.gov

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