The present study aims to evaluate the modification of functional capacity induced by an adapted physical activity program in subjects with haemophilia. The exercise program used aims to improve joint mobility, muscle strength, static and dynamic balance, motor coordination. The program is structured in 1 hour sessions of 2 days/week and lasts 6 months. The primary endpoint is the change in functional capacity calculated as the difference between the baseline assessment and the 3 and 6 month assessment of the 6 Minutes Walking Test measured with the G-Walk (BTS Bioengineering S.p.A).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
14
An exercise program to improve joint mobility, muscle strength, static and dynamic balance, motor coordination will be performed 2 times/week for 6 months.
Istituto Ortopedico Rizzoli
Bologna, Bo, Italy
6 Minutes Walking Test
The change in functional capacity calculated as the difference between the baseline 6 Minutes Walking Test assessment and the 3 and 6 month assessment measured with the G-Walk (BTS Bioengineering S.p.A).
Time frame: baseline,3 months,6 months
Functional Independence Score in Hemophilia (FISH)
It is a questionnaire which is carried out by an operator to evaluate autonomy in carrying out eight activities of daily life: personal hygiene, eating, dressing, transferring from chairs, squatting, walking, climbing stairs, running. Each activity is measured according to the amount of assistance needed to perform it.
Time frame: baseline,3 months,6 months
Hemophilia joint health score (HJHS)
It is a scale compiled by an operator to evaluate the health status of the joints. The HJHS measures joint health in the domains of body structure and function (biomechanics) of the structures most frequently affected by hemorrhage in patients with hemophilia: the knees, ankles, and elbows.
Time frame: baseline,3 months,6 months
Tampa Scale of Kinesiophobia - (TSK)
It is a questionnaire filled in by the patient to assess fear of movement. This scale is an international evaluation parameter with which a persistent and constant, completely unjustified concern in carrying out movements for fear of causing pain or damage is highlighted.
Time frame: baseline,3 months,6 months
Hemophilia Activity List (HAL)
It is a questionnaire filled in by the patient on activity limitations. The HAL scale measures the impact of haemophilia on functional abilities in adults. It is made up of 42 questions investigating 7 domains: 1. Lying / Sitting / Kneeling / Standing, 2. Leg functions, 3. Arm functions, 4. Transport, 5. Personal care, 6. Household activities, 7. Leisure and sporting activities.
Time frame: baseline,3 months,6 months
Balance - Single leg stand test
The test should be performed with eyes open and hands on the hips. Instruct the patient to stand on one leg unassisted, starting when the patient's foot leaves the ground and stopping the time the patient's foot touches the ground and/or when their hands leave the hips. Abnormal values may indicate conditions such as peripheral neuropathy, intermittent claudication, or other conditions that may impair balance
Time frame: baseline,3 months,6 months
Balance - Time Up and Go (TUG)
The TUG is a general physical performance test used to assess mobility, balance and locomotor performance in people with potential balance disturbances. More specifically, it assesses the ability to perform sequential motor tasks relative to walking and turning.
Time frame: baseline,3 months,6 months
Pain (VAS - Visual Analogue Scale )
Pain measured by VAS (Visual Analogue Scale) on target joint
Time frame: baseline,3 months,6 months
Muscle strenght- 30" Chair stand test
The purpose of this test in to evaluate leg strength and endurance, by counting the number of times the patient comes to a full standing position in 30 seconds
Time frame: baseline,3 months,6 months
Muscle strenght-Arm curl test
this test evaluates functional upper extremity fitness of adults, with the goal is to complete as many curls (through the entire available range of motion) in 30 seconds
Time frame: baseline,3 months,6 months
Muscle strenght- Hand held measuring of hip and knee flexors/extensors
Measure the muscle strenght of hip and knee flexors/extensors by using a Hand held
Time frame: baseline,3 months,6 months
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