Viscoelastic Properties of Respiratory and Peripheral Muscles of COPD Patients

Gaziantep Islam Science and Technology University60 enrolled

Overview

The aim of this study was to compare the viscoelastic properties of auxiliary respiratory muscles and peripheral muscles of chronic obstructive pulmonary disease patients with healthy subjects. Myotonometry was used to evaluate the viscoelastic properties of the muscles. The viscoelastic properties of the sternoclaidus mastoid, pectoralis major, upper trapezius, deltoid, biceps brachii, rectus femoris, gastrocinemius, and tibialis anterior muscles were evaluated.

muscle viscoelastic properties; muscle tone, stiffness and elasticity. These features may vary due to muscle overuse, lack of relaxation and recovery. The aim is to investigate these differences in COPD patients and healthy individuals.

Study Type

OBSERVATIONAL

Enrollment

Conditions

COPD Muscle Tone Abnormalities

Eligibility

Sex: MALEMin age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * male gender, * body mass index (BMI) between 18.5-29.9 kg/m2, * stable COPD patients Exclusion Criteria: * being in the acute exacerbation period for COPD patients, * having undergone any neurological, orthopaedic or thoracic surgery, * presence of malignancy in any organ, * presence of comorbidities affecting muscle atrophy (myasthenia gravis, muscular dystrophy, etc.).

Locations (1)

Gaziantep İslamic Science and Technology University

Gaziantep, Şahinbey, Turkey (Türkiye)

Outcomes

Primary Outcomes

Respiratory functions (PEF)

Peak expiratory flow (PEF) were measured was evaluated with spirometry. It will be recorded as liters and expected percentage

Time frame: 1 Day

The Medical Research Council Scale

Patients simply indicate on the scale the level of activity that causes dyspnoea in them according to the activities between 0-4.

Time frame: 1 Day

The COPD Assessment Test

This statement describes a scale consisting of eight items, each with response values ranging from 0 to 5. The total score is calculated by summing the responses to all the items, resulting in a range from 0 to 40. A higher total score indicates a greater negative impact of the disease on the individual's quality of life and daily activities.

Time frame: 1 Day

Viscoelastic properties of muscles

The viscoelastic properties of the muscles (muscle tone (Hz), and elasticity (Relative), stiffness (N/m)) were measured using a hand-held myotonometer.

Time frame: 1 Day

Respiratory functions (FEV1)

In pulmonary function test was evaluated with spirometry. forced expiratory volume in the first second (FEV1);will be recorded as liters and expected percentage

Time frame: 1 Day

Respiratory functions (FVC)

In pulmonary function test was evaluated with spirometry. forced expiratory volume in the first second (FEV1);will be recorded as liters and expected percentage

Time frame: 1 Day

Respiratory functions (FEV1/FVC)

ratio of forced expiratory volume in the first second to vital capacity (FEV1/FVC) was evaluated with spirometry.

Data from ClinicalTrials.gov

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