This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three. Patients with mental disorders who have been recruited will take their medication regularly for 1 year and participate in baseline and follow-up assessments.
The study seeks to identify possible biological markers of schizophrenia and the effects of gene-environment interactions on brain structural and functional networks. So we can help doctors and scientific researchers better understand the neuropathological basis of schizophrenia.
Study Type
OBSERVATIONAL
Enrollment
1,899
Patients with mental disorders should take the appropriate medicine as prescribed by the doctor，and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.
The Second Xiangya hospital of central south univerity
Changsha, Hunan, China
RECRUITINGcortical morphology
Data were obtained using magnetic resonance scans
Time frame: 40 minutes
target gene charaacteristics
10ml peripheral blood was extracted for gene analysis
Time frame: 1 day
scale scores
The score of each dimension and the total score were calculated according to the scale.The scale includes three dimensions: negative symptom, positive symptom and general psychopathology, and the score range of each dimension is different. The total score ranges from 30 to 210, with higher scores indicating worse results.
Time frame: 90 minutes.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.