The aim of this study is to investigate the prognostic value of Blood Urea Nitrogen to serum Albumin ratio in septic Acute Kidney Injury patients Follow-up will be conducted for all enrolled patients for 30 days from admission to record mortality and the cause of death.
A complete medical history will be obtained from all patients including age, sex, comorbidities, cause of sepsis, and SOFA and APACHE II scores at admission. Blood samples will be collected within 24 hours of AKI diagnosis for analysis of Blood Urea Nitrogen (BUN) and serum Albumin levels. Blood Urea Nitrogen to serum Albumin ratio (B/A) will be calculated by dividing the BUN of a patient by their serum Albumin levels. Laboratory parameters also will include pH, lactate (Lac), base excess (BE), hemoglobin (Hb), platelet (PLT) count, white blood cell (WBC) count, bilirubin, hematocrit (HCT), creatinine (Cr), serum sodium (Na), serum potassium (K), serum calcium (Ca), serum magnesium (Mg), triglyceride (TG), aspartate aminotransferase (ALT), alanine aminotransferase (AST), prothrombin time (PT), and activated partial thromboplastin time (APTT) values. Follow-up will be conducted for all enrolled patients for 30 days from admission to record mortality and the cause of death. Study population will be divided into survival and non-survival groups based on their 30-day survival status
Study Type
OBSERVATIONAL
Enrollment
64
Ain Shams University
Cairo, Abbassia, Egypt
mortality
number of cases of mortality
Time frame: 30 days
mechanical ventilation
number of participants who needed mechanical ventilation
Time frame: 30 days
stage-3 AKI
number of participants who developed stage-3 AKI
Time frame: 30 days
renal replacement therapy
number of participants who needed renal replacement therapy
Time frame: 30 days
septic shock
number of participants who developed septic shock
Time frame: 30 days
length of ICU stay
length of ICU stay in days
Time frame: 30 days
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