Fluid resuscitation is one of the cornerstones of treatment in ICU patients. Nonetheless, excessive fluid administration can lead to fluid overload which has been associated with worse outcomes in the ICU. To prevent this, assessments of fluid responsiveness are commonly employed. However, fluid responsiveness does not take fluid tolerance into account. Fluid tolerance is the idea that a patient might still be fluid responsive but might already be at risk of the detrimental effects of fluid therapy. Recent developments in point of care ultrasound e.g. the Venous excess ultrasound might help identify patients at risk of fluid overload. However its association with patient relevant outcomes in the ICU remains unclear.
This study will investigate the association between the venous excess ultrasound grading system (VExUS) and patient relevant outcomes such as acute kidney injury, mortality and length of stay. A secondary analysis is planned where the association between VExUS and the lung ultrasound score will be investigated
Study Type
OBSERVATIONAL
Enrollment
136
Amsterdam UMC
Amsterdam, North Holland, Netherlands
RECRUITINGRate of acute kidney injury
Clinically relevant acute kidney injury in the ICU: a 200% rise in creatinine or the use of renal replacement therapy
Time frame: within 30 days of admission to the ICU
Mortality
death of all causes
Time frame: within 30 days of admission to the ICU
Rate of MAKE-30
a composite endpoint of mortality and acute kidney injury ( including renal replacement therapy)
Time frame: within 30 days of admission to the ICU
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