The purpose of this study was to compare efficacy and side effects of two target delineation methods for stereotactic radiotherapy of metastatic spinal tumors.
The purpose of this study was to compare efficacy and side effects of two target delineation methods for stereotactic radiotherapy of metastatic spinal tumors. This is a bidirectional cohort study planned to enroll approximately 500 patients with metastatic spinal tumors. Patients are divided into two groups according to the target delineation method. Group 1：The target bolume only includes local tumor. Group 2：The target bolume includes local tumor and adjacent vertebral area.
Study Type
OBSERVATIONAL
Enrollment
500
Group 1(small target delineation)：The target bolume only includes local tumor. Group 2(small target delineation)：The target bolume includes local tumor and adjacent vertebral area.
Department of Radiation Oncology Cancer Center, Peking University Third Hospital 49# North Garden Rd.,Haidian Dist.
Beijing, Beijing Municipality, China
RECRUITINGDisease Control Rate（DCR）
Disease Control Rate（DCR），including complete response（CR），partial response(PR) and stable disease(SD ).
Time frame: 2 years
Pain relief rate
VAS Score(Visual Analog Scale Score) decreased after treatment
Time frame: 3 months
Incidence of side effects
radiation myelitis,radiation esophagitis, etc.
Time frame: 2 years
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