Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.
This is a cohort observational study. The target population for the trial will be men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were \< 18 years old, currently \> 18 years old to 50 years old and cancer in remission for at least 2 years. The testicular function, including sperm and hormonal functions, will be compared with aged-matched controls from men attending the Family Planning Association for premarital check-up.
Study Type
OBSERVATIONAL
Enrollment
200
Blood for FSH, LH, testosterone
Semen analysis
The European Male Ageing Study (EMAS) questionnaire
Queen Mary Hospital
Hong Kong, China
RECRUITINGSperm concentration
Sperm concentration
Time frame: up to 3 months
Semen parameters
Based on the WHO criteria
Time frame: up to 3 months
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