Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy

Sun Yat-sen University50 enrolled

Overview

To investigate the efficacy and safety of modified deep lateral wall decompression and/or medial wall decompression for Moderate-to-severe Grave's Ophthalmopathy.

The purpose of the study is to evaluate the effectiveness and complications of modified deep lateral wall decompression and medial wall decompression, in order to develop a standardized technical approach to the treatment of Moderate-to-severe Grave's Ophthalmopathy.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Graves Ophthalmopathy Surgery

Interventions

modified deep lateral and/or medial wall decompressionPROCEDURE

Modified deep lateral orbital wall decompression is based on traditional outer wall decompression with combined abrasion of the deep outer orbital wall (including the greater pterygoid wing) to achieve adequate enlargement of the orbital cavity.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. EUGOGO/NOSPECS grade was moderate-to-severe thyroid associate ophthalmopathy; 2. CAS≤3 score; 3. stable thyroid function for at least 6 months; 4. able and willing to participate in clinical trials and ensure regular follow-up; Exclusion Criteria: 1. any uncontrollable clinical problems (severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumors); 2. B-ultrasound or CT, MRI found other diseases causing exophthalmos (intraorbital space occupying lesion, inflammatory pseudotumor, neurofibroma, etc.); 3. uveitis, glaucoma, high myopia, diabetic retinopathy and other eye diseases 4. those who were considered by the researchers to be excluded

Locations (1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China

RECRUITING