The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions. Currently, the relationship between brain activity related to inhibitory control, executive functions, and dual-task walking performance in people with PD is not well understood. Therefore, this study aims to investigate the significance of different executive function domains on gait stability in healthy older adults and people with PD; whether brain activation related to inhibitory control is associated with gait stability in healthy older adults and people with PD.
Study Type
OBSERVATIONAL
Enrollment
70
Measurement of cognitive function, gait performance, and electroencephalogram
National Yang Ming Chiao Tung University
Taipei, Taiwan
RECRUITINGNational Yang Ming Chiao Tung University
Taipei, Taiwan
RECRUITINGGait variability
Using GAITRite system to measure the coefficient of variation (CV). The mean and standard deviation will be used to calculate the coefficient of variation (CV). CV = standard deviation / mean \* 100%
Time frame: 1 day
Gait speed
Using GAITRite system to measure gait speed.
Time frame: 1 day
Step length
Using GAITRite system to measure step length
Time frame: 1 day
Step width
Using GAITRite system to measure step width.
Time frame: 1 day
Single support time
Using GAITRite system to measure single support time
Time frame: 1 day
Double support time
Using GAITRite system to measure double support time
Time frame: 1 day
Frontal Assessment Battery
The score ranged from 0 to 18. Higher scores show better executive function.
Time frame: 1 day
Trail making test
Trail making test contain part A and part B. Faster completing the test indicates better executive function.
Time frame: 1 day
Stroop color and word test
Record numbers of corrected color words which the subject responds within 45 sec.
Time frame: 1 day
Digit span test
Digit span test contain forward and backward part. Scores of forward digit span ranges from 0 to 16. Score of backward digit span ranges from 0 to 14. Higher scores indicate better executive function.
Time frame: 1 day
Event-related potential - N2
Measure event-related potential through electroencephalography under single-task and dual-task paradigm.
Time frame: 1 day
Event-related potential - P300
Measure event-related potential through electroencephalography under single-task and dual-task paradigm.
Time frame: 1 day
Go/Nogo test
Behavioral test during measuring electroencephalography.
Time frame: 1 day
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