Four prospective observational studies of ventilation in critically ill patients were harmonized and pooled.
The individual data from four observational studies ('Epidemiology of Respiratory Insufficiency in Critical Care study' \[ERICC\], the 'Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure' \[LUNG SAFE\], 'PRactice of VENTilation in critically ill patients without ARDS' \[PRoVENT\], 'PRactice of VENTilation in critically ill patients in Middle-income Countries' \[PRoVENT-iMiC\]) were harmonized and pooled into a database named 'PRoPERLy II'. This database will be used to address various issues in diverse patient categories.
Study Type
OBSERVATIONAL
Enrollment
8,000
Patients were subjected to invasive ventilation.
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Amsterdam, Netherlands
Mortality.
Mortality risk based on PaO2/FiO2 or SpO2/FiO2.
Time frame: ICU visit, anticipated average 4 days
Predicted PaO2. SpO 2 /FiO 2 ratios and of predicted PaO 2 /FiO 2 ratios.
PaO2 values predicted from SpO2 values.
Time frame: In the first 4 days of invasive ventilation.
Predicted PaO2/FiO2 SpO 2 /FiO 2 ratios and of predicted PaO 2 /FiO 2 ratios.
PaO2/FiO2 predicted from SpO2/FiO2
Time frame: In the first 4 days of invasive ventilation.
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