The aim of this trial is to evaluate the efficacy and safety of HRS-7535 compared with dapagliflozin in subjects with type 2 diabetes mellitus with inadequate glycemic control using metformin.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
800
HRS-7535 tablet
dapagliflozin tablet
Beijing Hospital
Beijing, Beijing Municipality, China
RECRUITINGChange from baseline in HbA1c at 32 weeks of treatment
Time frame: at 32 weeks
Percentage of Participants Who Achieved HbA1c <7.0% at Week 32
Time frame: at 32 weeks
Percentage of Participants Who Achieved HbA1c ≤6.5% at Week 32
Time frame: at 32 weeks
Change from Baseline in Fasting Serum Glucose, from Baseline to Week 32
Time frame: at 32 weeks
Percentage Change from Baseline in Body Weight, from Baseline to Week 32
Time frame: at 32 weeks
Change from Baseline in Body Weight, from Baseline to Week 32
Time frame: at 32 weeks
Change from Baseline in Waist Circumference, from Baseline to Week 32
Time frame: at 32 weeks
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