Hyperglycemia and Acute Pancreatitis

Shanghai Changzheng Hospital4,500 enrolled

Overview

The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2. What are the related factors for PPDM-A? All patients with acute pancreatitis have been given standardized treatment for the condition. The researchers will compare the PPDM-A group with the non-PPDM-A group to find the risk factors for PPDM-A.

Investigators retrospectively collected data from patients with acute pancreatitis (AP) in participating centers between January 2013 and June 2024.

Study Type

OBSERVATIONAL

Enrollment

4,500

Conditions

Acute Pancreatitis (AP)Diabetes Mellitus

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with pancreatitis attending participating centers since January 2013 (patients with clinically reported AP (ICD-10:K85 or related diagnosis)); 2. Age between 18 and 80 years; 3. Patients have undergone glucose metabolic tests at least 1 month after discharge from hospital. Exclusion Criteria: 1. Patients with a history of diabetes mellitus prior to the AP attack; 2. Patients who underwent pancreatic surgery; 3. Patients with hereditary pancreatitis and autoimmune pancreatitis; 4. Patients with missing data regarding age or gender.

Outcomes

Primary Outcomes

Number of participants who have developed PPDM-A

PPDM-A was defined as diabetes after AP in the absence of a history of preexisting diabetes before the AP episode.

Time frame: From the AP treatment to 5 years after the end of treatment

Data from ClinicalTrials.gov

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