Comparison of IV Nalbuphine Versus Ibuprofen for Postoperative Pain Control in Cesarean Section

Muhammad Aamir Latif80 enrolled

Overview

The local data is insufficient to directly compare IV nalbuphine versus ibuprofen among people in this region. The findings of this study would add to the existing data and would be helpful for health providers to opt for a better option for postoperative pain relief following a cesarean section under general anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Pain Management

Interventions

IbuprofenDRUG

Patients were given 800 mg Ibuprofen in 200 cc normal saline intravenously at the time of arrival in the ward.

NalbuphineDRUG

Patients received 20 mg nalbuphine in 200 cc normal saline IV at the time of arrival in the ward.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Parturient females * Aged between 18-45 years * Gestational age above 32 weeks * ASA class I to II * Anticipated hospital stay for at least 24 hours Exclusion Criteria: * Known allergy to the drugs being evaluated in this study * Renal and/or hepatic impairment (as per medical record) * History of bronchial asthma or history or risk of intracranial hemorrhage (as per medical record) * Low platelets count (\<70000) or with bleeding diathesis * BMI above 30 kg/m2

Locations (2)

Nishtar Hospital

Multan, Punjab Province, Pakistan

Nishtar Medical University

Multan, Punjab Province, Pakistan

Outcomes

Primary Outcomes

Efficacy in pain control

Outcome was noted in the form of VAS pain scores. Scores from 1 to 3 were labeled as mild pain, 4 to 6 as moderate pain, and 7 to 10 as severe pain.

Time frame: At 1 hour, 3 hours, and 6 hours.

Data from ClinicalTrials.gov

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