This study aims to investigate the impact of short term, two distinct dietary interventions, namely the Keto diet and Intermittent Fasting on oral health by measuring the severity of: * Periodontal diseases (Gingivitis). * Oral health status (Plaque index). As well as measuring the impact of these different dietary pattern on the levels of C- Reactive Protein, IL-6, TNF-a in mean of inflammatory biomarkers as well as LL- 37 peptide as well as measuring salivary flow and ph. Objectives of the study 1. Evaluate the impact of Keto diet and Intermittent Fasting on oral health among the Iraqi population. 2. Assess changes in inflammatory biomarkers within the study groups before and after the intervention period. 3. Compare the effects of Keto diet and Intermittent Fasting on oral health and inflammatory biomarkers between the two intervention groups. 4. Examine the variations in oral health and inflammatory biomarkers within each group by comparing the baseline (Iraqi diet) and post-intervention stages. 5. Investigate the influence of Keto diet and Intermittent Fasting on the levels of LL37, an antimicrobial peptide.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
52
They were advised to eat ad libitum but to limit their carbohydrate intake to a maximum of 20-40 g/day to derive at leasut 75%, 15-20%, and 5-10% of total energy from fats, protein, and carbohydrates, respectively.
The 16/8 TRF group was asked to consume their daily calorie intake during an 8-hour window during the daytime and then fast for the remaining 16 hours each day throughout the intervention period.
University of Mustansiriyah
Baghdad, Street 6, Iraq
effect of keto diet on oral health
effect of keto diet on oral health by measuring the plaque index and bleeding on probing index
Time frame: 30 days
effect of intermittent fasting on oral health
effect of intermittent fasting on oral health by measuring the plaque index and bleeding on probing index
Time frame: 30 days
The effect of keto diet on salivary inflammatory biomarkers
effect of keto diet on salivary inflammatory biomarkers ( IL-6, IL-1B, C-RP, TNF-A, LL-37)
Time frame: 30 days
The effect of intermittent fasting on salivary inflammatory biomarkers
effect of intermittent fasting on salivary inflammatory biomarkers ( IL-6, IL-1B, C-RP, TNF-A, LL-37)
Time frame: 30 days
comparing the effect of KD and IF on inflammatory biomarkers
comparing the effect of keto diet and intermittent fasting on salivary inflammatory biomarkers ( IL-6, IL-1B, C-RP, TNF-A, LL-37)
Time frame: 30 days
comparing the effect of KD and IF on oral health
comparing the effect of KD and IF on oral health by measuring the plaque index and bleeding on probing index
Time frame: 30 days
The effect of intermittent fasting on bodyweight
The effect of intermittent fasting on bodyweight loss for overweight and obese cl I participants
Time frame: 30 days
The effect of keto diet on bodyweight loss
The effect of keto diet on bodyweight loss for overweight and obese cl I participants
Time frame: 30 days
The effect of keto diet on salivary PH
The effect of keto diet on salivary PH ( an increase or decrease)
Time frame: 30 days
The effect of intermittent fasting on salivary PH
The effect of intermittent fasting on salivary PH ( an increase or decrease)
Time frame: 30 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.