Acute Kidney Injury and Recovery Mode in Pediatric Liver Transplantation

Tianjin First Central Hospital700 enrolled

Overview

Acute kidney injury (AKI) is a common complication after pediatric liver transplantation (PLT), and renal impairment after LT has proven to be related with increased graft failure and mortality. The recovery mode of kidney injury after PLT has not been systematically studied. Therefore, in this study the investigators aimed to systematically evaluate prognosis of AKI after PLT, combine the recovery mode of AKI with related risk factors, and establish a relationship between AKI and CKD.

Study Type

OBSERVATIONAL

Enrollment

700

Conditions

Postoperative Acute Kidney Injury Pediatric Liver Transplantation

Interventions

No Intervention: Observational CohortOTHER

no intervention

Eligibility

Sex: ALLMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who received a liver transplant for the first time. * Patients who were younger than 18 years of age at the time of transplant. Exclusion Criteria: * Patients with incomplete clinical data. * Patients with less than 5 years of follow-up. * Patients who have combined multiple solid organ transplants. * Patients with preoperative renal impairment (eGFR\<60ml/min/1.73 m2 or prior renal replacement therapy).

Locations (1)

Tianjin First Central Hospital

Tianjin, China

Outcomes

Primary Outcomes

Graft survival

Loss of graft is defined as patient death or secondary transplantation

Time frame: Based on the most recent follow-up before December 31, 2023. The investigators collected clinical data of patients from 2014 to 2018, and followed enrolled participants until at least 5 years after surgery

Data from ClinicalTrials.gov

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