To explore the effect of thymosin alpha 1 (Tα1) on postoperative peripheral blood circulating tumor cells and immunosenescence in patients with early-stage non-small cell lung cancer (NSCLC).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
40
subcutaneous injection of Tα1, 1.6mg each time, biw, for 3 months
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, Beijing Municipality, China
RECRUITINGNumber of CTCs
Number of peripheral blood circulating tumor cells after Tα1 treatment
Time frame: 4 months after sugery
Number of immune cells
Number of TERT+ immnue cells after Tα1 treatment
Time frame: 4 months after sugery
Peripheral blood immune cells profile
Number of immune cells profile, including but limited to CD4+, CD8+, T cells
Time frame: 4 months after sugery
AE
the safety profile of the Tα1 treatment
Time frame: within 4 months after sugery
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