In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median sternotomy. For this purpose, the investigators aimed to compare the hemodynamic responses to surgical incision and sternotomy and, pain intensity, total analgesic consumption, additional analgesic requirements of the patients in the first 24 hours after extubation under postoperative patient-controlled analgesia (PCA) adminisration.
Forty-six patients aged 18-70 years, ASA class I-III, who undergo CABG surgery were included in our study. The patients were randomized into the TTKPB group and the control group. Heart rate (HR) and mean arterial pressure (MAP) were recorded before peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy. PCA with tramadol was applied after extubation and "Numeric rating scale" NRS scores, total tramadol consumption, number of requests and additional analgesic requirements were recorded at 0, 1, 2, 4, 8, 12 and 24 hours.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
46
Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes
Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes
Istanbul University-Cerrahpasa
Istanbul, Fatih, Turkey (Türkiye)
Numeric Rating Scale (NRS) at rest
Numeric Rating Scale (NRS) for postoperative pain
Time frame: Postoperative 24 hours
Numeric Rating Scale (NRS) during coughing
Numeric Rating Scale (NRS) for postoperative pain
Time frame: Postoperative 24 hours
Mean arterial pressure
Postoperative 0, 1, 2, 4, 8, 12 and 24 hours
Time frame: Postoperative 24 hours
Heart rate
Postoperative 0, 1, 2, 4, 8, 12 and 24 hours
Time frame: Postoperative 24 hours
Mean arterial pressure
Peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy.
Time frame: Peroperative
Heart rate
Peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy.
Time frame: Peroperative
Bispectral Index (BIS)
Peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy.
Time frame: Peroperative
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