Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.

N/AActive Not RecruitingNCT06601985

Shanghai 10th People's Hospital154 enrolled

Overview

The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023. The practice of anal preservation surgery for ultra-low rectal cancer is being adopted gradually. Ultra-low rectal cancer patients who have undergone anal preservation are at an increased risk of developing significant bowel complications. The objective of this study was to examine the relationship between the type of bowel reconstruction following anal preservation surgery, and the subsequent outcomes of bowel function, quality of life and complication rates in patients with ultra-low rectal cancer.

Study Type

OBSERVATIONAL

Enrollment

154

Conditions

Rectum Cancer Faecal Incontinence Faecal Incontinence with Faecal Urgency Low Anterior Resection Syndrome Leakage, Anastomotic

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. A confirmed diagnosis of intestinal cancer, with the lower edge of the tumour \&lt;5 cm from the anus or \&lt;3 cm from the dentate line, and treated with anus-preserving surgery; 2. No distant metastasis; 3. Age \&gt;18 years old; 4. Voluntary enrollment in the study and signing of an informed consent. Exclusion Criteria: 1. A combination of severe cardiopulmonary, hepatic, renal, and other underlying diseases with a greater anaesthetic risk (ASA ≥ grade 4); 2. preoperative anal stenosis and anal nonfunction; 3. temporary stoma diversion.

Outcomes

Primary Outcomes

LARS score

The LARS scale has five questions with a total score of 42. A score of 0-20 lacks diagnostic value for LARS, while a score of 21-29 indicates mild LARS and a score above 29 indicates major LARS.