The goal of this clinical trial is to evaluate the relationship between obesity and gingival crevicular fluid resistin and adiponectin in periodontitis patients as well as assess the effect of non-surgical periodontal therapy on their levels using ELISA in obese individuals. Researchers will compare different stages of periodontitis to see if degrees of inflammation and periodontal therapy related obesity
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
60
Supragingival scaling was performed by Ultrasonic Scaler and manual scaling by sickle scaler . Subgingival scaling and root planing were accomplished with either universal or area specific Gracey curettes
Gingival crevicular fluid (GCF) samples were gathered and relocated in phosphate buffer saline inside Eppendorf tube then t they were manipulated by commercially available enzyme-linked immuno-sorbent assay
Faculty of Dental Medicine, Al-Azhar University Assiut Branch
Asyut, Asyut Governorate, Egypt
adiponectin level in gingival crevicular fluid
Time frame: From enrollment to the end of treatment results assessment at 12 weeks
resistin level in gingival crevicular fluid
Time frame: From enrollment to the end of treatment results assessment at 12 weeks
O'Leary Plaque score
Time frame: From enrollment to the end of treatment results assessment at 12 weeks
bleeding on probing percentage (BoP)
Time frame: From enrollment to the end of treatment results assessment at 12 weeks
clinical attachment level (CAL)
Time frame: From enrollment to the end of treatment results assessment at 12 weeks
probing pocket depth
Time frame: From enrollment to the end of treatment results assessment at 12 weeks
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