The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in patients hospitalized with stroke or stroke-like episodes (e.g., transient ischemic attack, TIA). The main questions this investigation aims to answer are: * Can different, independent providers reliability quantify motion pattern problems using a systematic approach called, The Functional Pathology of the Musculoskeletal System (FPMSS) model? * Are there differences in joint(s) motion patterns among asymptomatic volunteers, patients with TIA (people with brain disease without new neurologic disability), and recent ischemic stroke (patients with new stroke-related-disability, e.g., paralysis)? * Is there an association between joint(s) motion impairment severity and stroke survivor outcomes? Participants (asymptomatic and those with stroke) will undergo a set of repeated paired, musculoskeletal physical exams by independent providers blinded to each other's assessments and patient information. Researchers will compare the severity, location, and quantity of joint(s) motion impairment between these three groups with the physical examination methodology (FPMSS). Clinical information (e.g., test results, diagnoses, brain imaging, medical history) will be collected from patients admitted for TIA and stroke. Enrolled participants with recent stroke will complete a survey three months after hospitalization to determine their self-perceived quality-of-life.
Study Type
OBSERVATIONAL
Enrollment
120
University of California Davis Medical Center
Sacramento, California, United States
RECRUITINGExaminer Rater-Reliability
Test intra- and inter-rater reliability in identifying osteopathic somatic dysfunction (joint(s) motion impairment) among asymptomatic volunteers, patients with TIA, and recently admitted patients with stroke.
Time frame: 3 to 14 days
Functional Pathology of the Musculoskeletal System
A total of 80 specific musculoskeletal examination tests are performed assessing the amount of available motion in the spine, upper extremities, lower extremities, and pelvis. Navigational Motions (i.e., whole upper limb motion at shoulder) are scored on a scale of 1-4 with one representing the least loss of motion and 4 representing the most and Component Motions (i.e., motion of foot at ankle) scored on a scale of 0-3 with 0 representing "normal motion" and 3 representing "no motion".
Time frame: 3-14 days
National Institutes of Health Neuro-Quality of Life (QoL) survey
Quantify self-reported health-related quality-of-life (QoL) 90 days after ischemic stroke. Patient response domain scores have a normative distribution and are compared against general population means (50, with a standard deviation of 10; range 10-90). Interpreting value responses above or below means are based on the specific questions - i.e., higher scores do not uniformly reflect improvement while lower scores do not necessarily reflect poorer status. Patient will receive a digitally distributed survey inquiring about QoL domains surrounding mobility, satisfaction with and ability to participate in social roles, mood, fatigue, anxiety, cognition.
Time frame: 90 days
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