To control post-operative pain, multiple drugs are available, and in the western countries opioids are preferred. However, they have their own side effects, and so to reduce their dependence, multiple adjuncts are used. We compared the use of opioids vs just non steroidal anti-inflammatory drugs on post-operative pain control following inguinal hernia surgery
Inguinal hernia repair is one of the most common surgeries performed by general surgeons worldwide. The preferred procedure for primary open inguinal hernias is open mesh repair (tension-free)-also called Lichtenstein repair. Opioids remain the mainstay for post-operative analgesia, however, they have a tendency for dependence along with other side effects. Non-steroidal anti-inflammatory drugs (NSIADs) have been used as adjuncts to decrease the use of opioids, however, usually NSAIDs are not used in isolation following surgery. We compared post-operative analgesia following primary open inguinal hernia repair, with patients receiving only opioids vs patients only receiving NSAIDs. 60 patients were randomized in to 2 groups. Group A patients received tramadol injection (opioid) every 8 hours, while patients in Group B received injection ketorolac (NSAID) every 8 hourly. Pain was measured using visual analogue score at 2-, 6-, 12- and 24-hours following surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
60
Patients in Group A received injection tramadol 50mg intravenously every 8 hours following surgery. Patients in Group B received injection ketorolac 30mg intravenously every 8 hours following surgery.
Pakistan Air Force Hospital
Islamabad, Capital Territory, Pakistan
Visual analogue scale - pain score
Visual analogue score to quantify pain following laparoscopic cholecystectomy. Maximum value is 10 (which means worst pain), and minimum value is 0 (which means no pain).
Time frame: 2-, 6-, 12-, 24-hours following surgery
Flatus
Time to passing flatus
Time frame: within 24 hours following surgery
nausea/vomiting
time when nausea/vomiting was not present in the patient
Time frame: within 24 hours following surgery
Time to ambulation
time after surgery when the patient started ambulating
Time frame: within 24 hours following surgery
rescue analgesia
number of times rescue analgesia was used
Time frame: within 24 hours following surgery
Mean arterial pressure
systolic and diastolic blood pressures were measured for the patients at intervals, and then mean arterial pressures were calculated
Time frame: 2-, 6-, 12-, 24-hours following surgery
Heart rate
Heart rate was measured at intervals in beats per minute
Time frame: 2-, 6-, 12-, 24 hours
oxygen saturation
oxygen saturation was noted at intervals
Time frame: 2-, 6-, 12-, 24 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.