The goal of this clinical trial is to learn if inspiratory muscle training facilite the liberation of mechanical ventilation. The main questions it aims to answer are: Does inspiratory muscle training facilitate weaning from mechanical ventilation and enhance muscle strength in critically ill, subacute adult patients? The main questions it aims to answer are: Does pulmonary rehabilitation facilitate wwaning form mechanical patients? Does the intervention improve respiratory muscle strength and respiratory patterns? Participants received: Inspriatory muscle training twice daily for three consecutive weeks or until the subject no longer required ventilator support.
Patients on mechanical ventilation often experience rapid diaphragm atrophy on the second day, resulting in muscle fiber changes, respiratory muscle weakness. Clinical studies have explored enhancing diaphragm and respiratory muscle strength and endurance through inspiratory muscle, expiratory muscle, and combined respiratory muscle training. This study was to determine if inspiratory muscle training significantly facilitates liberation from mechanical ventilation and improves muscle strength when compared to without IMT among subacute critically ill adult patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
A threshold inspiratory muscule device used a starting resistance set at 30% maximum inspiratory pressure, connecting to subject artificial airway. The subjects were then instructed to perform fast and forceful inspirations against added inspiratory resistance. The inspiratory muscle training was conducted twice daily over five consecutive days, followed by a two-day rest period. This regimen continued for three consecutive weeks or until the subject no longer required ventilator support.
Subjects received routine care without intervention.
Zuoying Armed Forces General Hospital
Kaohsiung City, Taiwan
Number of days until liberation from mechanical ventilation
A record of the number of days until liberation from mechanical ventilation.
Time frame: Three weeks
Maximum inspiratory pressure
Maximum inspiratory pressure was measured by having each subject exert maximum inspiratory force against a pressure gauge.
Time frame: Three weeks
Maximum expiratory pressure
Maximum expiratory pressure was measured by having each subject exert maximum expiratory force against a pressure gauge.
Time frame: Three weeks
Peak expiratory flow
The peak expiratory flow was measured using a respiratory mechanics monitor during three forceful expirations.
Time frame: Three weeks
Peak inspiratory flow
The peak inspiratory flow was measured using a respiratory mechanics monitor during three forceful expirations.
Time frame: Three weeks
Rapid Shallow breathing index
The RSBI was calculated by dividing the respiratory rate by the tidal volume
Time frame: Three weeks
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