Leucocyte subpopulation and platelet indices analysis can predict clinical outcome
Study Type
OBSERVATIONAL
Enrollment
422
Mina Maher Raouf
Minya, Egypt
Sensitivity and specificity of either leucocyte profiling , platelet indices with early clinical deterioration
SOFA increase 2 points or more, or development of septic shock, or mortality. leukocyte profile versus platelet indices. Early deterioration was defined as any of the above mentioned events occurring for the first time from T0 until (through) second calendar day. T0 was the biomarker sampling immediately after sepsis diagnosis. Timing of deterioration was subclassified from To to second calendar day ( any deterioration events for the first time from T0 until second calendar day after that defined as very early deterioration) or early deterioration ( from third calendar day to day-5 = any deterioration events occur for the first time only from third to the fifth calendar day inclusive after T0
Time frame: from biomarker sampling through fifth calendar day
association between leucocytes at enrollment with ICU mortality
Time frame: 2 weeks ( during ICU admission)
association between platelet indices at enrollment with ICU mortality
Time frame: 2 weeks (during ICU admission)
association between platelet indices at enrollment with incidence of mechanical ventilation
Time frame: 2 weeks
association between leucocytes at enrollment with incidence of mechanical ventilation
Time frame: 2 weeks (during ICU admission)
association between leucocytes at enrollment , with incidence of acute kidney injury
Time frame: 2 weeks (during ICU admission)
association between platelet indices at enrollment with incidence of acute kidney injury
Time frame: 2 weeks (during ICU admission )
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