The goal of this clinical trial is to learn if preparing the target alignment of the operative side in total knee arthroplasty (TKA) based on the non-arthritic side will give the patient better overall alignment, function, and improved results compared to basing our implant alignment and positioning off the arthritic side, which is currently the traditional method. The main questions it aims to answer are: * Will a patient have improved postoperative TKA results if the implant alignment is based off the non-arthritic side compared to the standard arthritic side? * What are the similarities or differences between study arms with respect to final implant alignment and positioning angles? Researchers will compare the outcomes of two cohorts of patients undergoing primary robotic-assisted total knee arthroplasty (RA-TKA) with normal contralateral knee. Based on preoperative CT imaging, the researchers will use normal contralateral side joint numbers as the target alignment for one group (Experimental arm) and utilize the traditional method for the other group (Active comparator arm). Clinical outcomes and patient-reported outcome measures (PROMs) will be compared between groups. Participants will: * Be randomized into one of two study arms and will receive either a unilateral knee CT or bilateral knee CT preoperatively * Follow-up in the clinic at 2 weeks, 6 weeks and 1-year postoperatively, per standard-of-care for x-ray and clinical evaluation. * Complete postop questionnaires (PROMs) at the prescribed follow-up intervals
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
1
Intervention given to the Active Comparator arm
Intervention given to the Experimental Arm
UofL Health
Louisville, Kentucky, United States
Overall Satisfaction
Overall Satisfaction with TKA using a Likert scale
Time frame: 1-year postoperatively
Pain VAS
Level of knee pain (scale of zero to ten) using the Visual Analog Scale (VAS)
Time frame: preoperatively, 6 weeks (± 2 weeks), and 1-year postoperatively
KOOS JR
KOOS JR questionnaire
Time frame: preoperatively, 6 weeks (± 2 weeks), and 1-year postoperatively
Forgotten Joint Score
FJS-12 questionnaire
Time frame: preoperatively, 6 weeks (± 2 weeks), and 1-year postoperatively
PROMIS-10 Mental and Physical Health scores
PROMIS-10 Global Health questionnaire
Time frame: preoperatively and 1-year postoperatively
Incidence of revision TKA
postoperative complication requiring a revision total knee arthroplasty
Time frame: 1 year postop
non-revision complication
postoperative complication requiring a non-revision procedure
Time frame: 1 year postop
Active ROM
Active knee range of motion: active extension, active flexion
Time frame: preoperatively, 6 weeks (± 2 weeks), and 1-year postoperatively
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