The goal of this observational study is to investigate the prevalence and persistence of phantom limb pain (PLP) among amputees who experienced limb loss due to injuries sustained during the 2023 Türkiye earthquake. The main questions it aims to answer are: What is the prevalence of phantom limb pain among earthquake-related amputees at different follow-up intervals? How do different pain management strategies, such as regional analgesia versus intravenous analgesia, affect the severity and persistence of phantom limb pain? Researchers will compare participants receiving regional analgesia to those receiving intravenous analgesia to see if regional techniques are associated with lower rates of phantom limb pain and improved quality of life. Participants will: Complete pain assessments using standardized questionnaires at 1 week, 3 months, 6 months, and 12 months post-amputation. Provide information on their pain management experiences and the impact on their daily activities.
This observational study aims to assess the prevalence, characteristics, and management of phantom limb pain (PLP) among individuals who underwent amputations due to injuries sustained during the 2023 Türkiye earthquake. Conducted at the Mersin University Pain Clinic, the study involves 39 patients who were followed for 12 months post-amputation. The primary focus is to evaluate how different analgesic methods, such as regional versus intravenous analgesia, influence the development and persistence of PLP and associated phantom limb sensations (PLS). Patients were recruited from those treated at Mersin University Hospital immediately following the earthquake. Inclusion criteria included individuals aged 5 years and older who experienced amputation due to earthquake-related trauma. Exclusion criteria included pre-existing psychiatric disorders, history of neuropathic pain in the amputated limb, or inability to communicate due to cognitive impairment. The study's primary outcomes are the prevalence of PLP and PLS at 1 week, 3 months, 6 months, and 12 months post-amputation. Pain intensity is measured using the Visual Analog Scale (VAS), and the impact of different analgesic techniques on pain severity and quality of life is analyzed. Secondary outcomes include the incidence of residual limb pain and the effectiveness of various pain management strategies in reducing pain symptoms over time. This study is expected to contribute valuable insights into the management of PLP in disaster-related amputees, providing evidence to guide clinical practice and improve patient outcomes in similar post-disaster settings.
Study Type
OBSERVATIONAL
Enrollment
39
Regional analgesia techniques like epidural or peripheral nerve blocks.
IV medications used for pain control, including opioids and non-opioid analgesics.
Mersin University Faculty of Medicine
Mersin, Yenişehir, Turkey (Türkiye)
Prevalence of phantom limb pain
The percentage of amputee patients reporting PLP at each follow-up interval. PLP will be categorized as mild, moderate, or severe based on VAS scores.
Time frame: 1 week, 3 months, 6 months, and 12 months
o Prevalence of phantom limb sensations
The frequency of non-painful PLS such as tingling, itching, or movement sensations reported by patients at each follow-up period
Time frame: 1 week, 3 months, 6 months, and 12 months
Incidence of residual limb pain
The number of patients reporting RLP at each follow-up interval, categorized based on VAS scores.
Time frame: 1 week, 3 months, 6 months, and 12 months
o Impact of Analgesic Methods
The effect of different analgesic methods on the prevalence and severity of PLP and PLS. Outcomes will be analyzed to determine which analgesic method is associated with lower pain scores and fewer phantom sensations.
Time frame: 1 week, 3 months, 6 months, and 12 months
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