The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adult participants with advanced solid tumors.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
416
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Number of participants with adverse events (AEs)
Time frame: Up to 3 years
Number of participants with serious adverse events (SAEs)
Time frame: Up to 3 years
Number of participants with AEs meeting protocol defined dose-limiting toxicity (DLT) critera
Time frame: Up to 3 years
Number of participants with AEs leading to discontinuation
Time frame: Up to 3 years
Number of participants with AEs leading to death
Time frame: Up to 3 years
Number of DLTs that occur during the DLT evaluation period
Time frame: Up to 3 weeks
Maximum observed serum concentration (Cmax)
Time frame: Up to 3 years
Time of maximum observed concentration (Tmax)
Time frame: Up to 3 years
Area under the concentration-time curve from time zero to time of last quantifiable concentration (AUC(0-T))
Time frame: Up to 3 years
Area under the serum concentration-time curve within a dosing interval (AUC(TAU))
Time frame: Up to 3 years
Objective response rate (ORR)
Time frame: Up to 2 year
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
CONTACT
First line of the email MUST contain NCT # and Site #.
CONTACT
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Specified dose on specified days
Specified dose on specified days
University of Alabama at Birmingham
Birmingham, Alabama, United States
RECRUITINGUniversity of Miami Hospital and Clinics, Sylvester Cancer Center
Miami, Florida, United States
RECRUITINGLocal Institution - 0125
Maywood, Illinois, United States
NOT_YET_RECRUITINGLocal Institution - 0065
Iowa City, Iowa, United States
NOT_YET_RECRUITINGJohn Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey, United States
RECRUITINGCleveland Clinic
Cleveland, Ohio, United States
RECRUITINGLocal Institution - 0102
Columbus, Ohio, United States
NOT_YET_RECRUITINGLocal Institution - 0052
Portland, Oregon, United States
NOT_YET_RECRUITINGLocal Institution - 0090
Portland, Oregon, United States
NOT_YET_RECRUITINGLocal Institution - 0014
Pittsburgh, Pennsylvania, United States
WITHDRAWN...and 53 more locations