The goal of this clinical trial is to learn if CoQ10 amplifies endurance training-induced myokine and exerkine secretion and if those changes influences cognition in long-distance runners. Does 4-week high-dosage CoQ10 supplementation increase the secretion of myokine, exerkine sercetion? Does the above-mentioned intervention improve the cognitive function in long distance runners? Participants will: Take CoQ10 or a placebo every day for 4 weeks. Visit the laboratory once every 4 weeks for checkups and tests. Keep the participants' food and training diary.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
Long-distance runners will be supplemented with CoQ10 for 4 weeks in cross-over manner with 4 weeks of wash out period.
Long-distance runners will be supplemented with placebo for 4 weeks in cross-over manner with 4 weeks of wash out period.
Gdansk University of Physical Education and Sport
Gdansk, Poland
RECRUITINGChange in cognitive funtions as a result of CoQ10 supplementation measured via cogntitive function test.
The investigators assume that supplementation with CoQ10 will change cognition (measured via cognitive function tests - Stroop Test, Trial Making Test A and Trial Making Test B) in long-distance runners. The results will be obtained as time (seconds) needed to complete tasks while testing.
Time frame: The investigators are going to check this hypothesis after 4 weeks of high-dose supplementation with CoQ10
Change in myokine and exerkine concentration in the blood plasma as a result of CoQ10 supplementation.
The investigators will assess the concentration of blood myokine and exerkine concentration (pg or ug/dl) of blood plasma using the colorimetric method.
Time frame: The investigators are going to check this hypothesis after 4 weeks of high-dose supplementation with CoQ10
Change in aerobic capacity measured via direct test to volitional exhaustion on a motorized treadmill
The investigators assume that supplementation with CoQ10 will change the aerobic capacity (oxygen uptake in ml-1 x min-1 x kg-1) in long-distance runners. The determination of aerobic capacity will be done through progressive test to volitional exhaustion on a motorized treadmill and gas analyzer
Time frame: The investigators are going to check this hypothesis after 4 weeks of high-dose supplementation with CoQ10
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