Access BNP Clinical Enrollment Study

Inclusion Criteria: * Ability to provide informed consent * Adult greater than or equal to 22 years old, any gender, race, ethnicity * Presenting with clinical suspicion of new onset heart failure or worsening symptoms suggestive of decompensated or exacerbated heart failure * Ability to fulfill study data collection requirements (including responding to questions for the NYHA evaluation) Exclusion Criteria: * Individuals less than 22 years old * Impairment in individual's capacity to give informed consent * Dyspnea clearly not secondary to heart failure (e.g., primary lung disease or chest trauma). * On dialysis * On nesiritide infusion * Subject clinical/medical history access is not available to Sponsor, delegates, and FDA or other regulatory agencies upon request. * Active participation in a clinical study that may interfere with participation in this study (e.g., investigational drug study) * Reason(s) determined by the Principal Investigator that would place the individual at increased risk or preclude the individual from fully complying with or completing the study.