The aim of this study to determine the optimal dose of dexmedetomidine as an adjuvant to bupivacaine in U.S guided TAP block for preemptive analgesia In patients undergoing lower abdominal cancer surgeries.
The transversus abdominis plane (TAP) involves innervations of the anterolateral abdominal wall derived from T6-L1. The block can be given either by anatomical landmark technique or by using an ultrasound probe. The local anesthetic is deposited in a plane between internal oblique and transversus abdominis muscle. It provides adequate postoperative analgesia following various abdominal surgeries.Dexmedetomidine is an alpha-2 agonist that has been approved as a venous sedative and an adjuvant for pain relief .In previous studies, the addition of dexmedetomidine to bupivacaine in the TAP block has prolonged the effect of this block . So far, the optimal dose of dexmedetomidine for the TAP block has not been determined.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
The analgesic effect of Two different doses of dexmedetomidine as adjuvent to bupivacaine in tap block
South egypt cancer institute,Assiut University
Asyut, Egypt
Total morphine consumption during the first 24 hours postoperatively
Morphine consumption during the First 24 hours postoperative
Time frame: First 24 hours postoperative
Severity of pain using Visual analogue scale
The severity of pain at rest and on coughing will be assesd using a 10-cm vas(0 means no pain ,10 means worst pain)
Time frame: First 24 hours postoperative
Patient level of sedation using four point modified ramsy scale
using a 4-point scale (0 = awake and alert, 1 = minimally sedated, responds to speech, 2 = moderately sedated, arousable by tactile stimulation, and 3 = deeply sedated, arousable only by painful stimulation)
Time frame: First 24 hours postoperative
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