Microbiota and Carcinogenesis of Small-intestine Neuroendocrine Tumors

Hospices Civils de Lyon75 enrolled

Overview

The aim of the study is to investigate the impact of the microenvironment on tumorigenesis of small intestinal neuroendocrine tumors often located in the terminal ileum, without identified driver mutations.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Small-intestine Neuroendocrine Tumors

Interventions

Blood and stool samplingOTHER

Blood and stool sampling

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with one or more small-intestine neuroendocrine tumor with indication of surgery * Patient with consent for the collection, storage and reuse of data associated with his/her disease * Age ≥ 18 years at the time of inclusion * Non-objection statement obtained for participation in the study Exclusion Criteria: * Patients with poorly differentiated neuroendocrine carcinoma or NET (neuroendocrine tumors) of non-intestinal origin or mixed tumors (MiNEN) * Pregnant, parturient or breast-feeding women * Minors * Persons deprived of liberty by judicial or administrative decision * Adults under legal protection (guardianship, curatorship)

Locations (1)

Edouard Herriot University Hospital

Lyon, France, France

RECRUITING

Outcomes

Primary Outcomes

Composition of microbiota

Determination of the composition of blood, fecal, intra- and peri-tumoral microbiota in patients undergoing surgery for small-intestine neuroendocrine tumor.

Time frame: At day 1 and month 3

Central Contacts

Thomas WALTER, MD, PhD

CONTACT

0472117398 thomas.walter@chu-lyon.fr

Data from ClinicalTrials.gov

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