This clinical trial aims to study the interest of the Pleth Variability Index (PVI) to evaluate perioperative fluid responsiveness in neurosurgery in adults. The main question it aims to answer is: • Does the Pleth variability index predict fluid responsiveness in neurosurgery? Researchers will compare the Pleth variability index to dela PP to see if it predicts fluid responsiveness in neurosurgery. Once participants give their consent, they will be randomly assigned to one of two groups. In one group, fluid responsiveness will be monitored using the Pleth Variability Index, while in the other group, it will be monitored using delta PP.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
70
Perioperative fluid challenge and responsiveness will be based on monitoring the pleth variability index. In fact, volemia will be estimated with the PVI.
fluid challenge and responsiveness during intervention will be based on monitoring delta PP.
National Institute of Neurologie Mongi Ben-Hamida
Tunis, Tunisia
Value of PVI in fluid responsiveness in neurosurgery
Investigate the value of the plethysmographic variability index (PVI) in assessing the response to perioperative vascular filling in neurosurgery.
Time frame: chanfe of PVI value from baseline to a value more than 14% and untill the end of surgery
Amount of fluids administered intraoperatively
Time frame: during the surgery
Renal, metabolic and hydroelectrolytic repercussions.
Time frame: up to the first 24 hours postoperatively
Length of postoperative stay
Time frame: up to hospital discharge, an average of 4 days
Incidence of post-operative complications
Time frame: up to hospital discharge, an average of 4 days
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