The objective of this human study is to determine if the metabolic benefits observed with other anthocyanin-rich berries extend to elderberries. To accomplish this, we performed a short-term controlled feeding study in overweight but healthy volunteers in a placebo-controlled crossover clinical trial. Major study endpoints included blood glucose and insulin response to a high-carbohydrate meal challenge, indirect calorimetry, and profiling of the fecal microbiome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
18
Participants will consume elderberry juice 1-week.
Participants will consume placebo beverage twice/day for 1-week.
Washington State University
Spokane, Washington, United States
Substrate oxidation
Participants will be monitored by a metabolic cart at rest and while walking
Time frame: 3.5 hours
Glucose tolerance/insulin sensitivity
Blood will be collected following a meal tolerance test
Time frame: 3 hours
Gut Microbiome analysis
Feces will be collected before and after the intervention
Time frame: 5 minutes
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