The goal of this randomized clinical trial is to learn if imagining fast or slow muscle contractions causes different responses for nervous system excitability and muscle function in young, healthy males and females in. The main questions are: Does imagining fast muscle contractions cause greater nervous system excitability compared to imagining slow muscle contractions? Does imagining fast muscle contractions increase muscle function compared to imagining slow muscle contractions? A control condition (rest) will be compared with two intervention conditions: imagining fast and imagining slow conditions, to determine if the fast and slow increase outcomes more than control and if fast has the greatest response. Participants will: * Attend 4 laboratory visits * Perform 50 imagined contractions fast or slow, but with no physical movement * Physical muscle contractions and non-invasive brain stimulation would be completed before and after each condition.
Participants will complete 4 laboratory visits in a randomized order, including a familiarization session, a control condition, and 2 conditions involving imaginary muscle contractions. During visits involving imaginary muscle contractions, participants will complete 2 sets of 25 repetitions of either fast (i.e., less than 1 second to peak torque increase torque as fast as possible) or slow (i.e., 3 seconds to peak torque) isometric elbow flexions. Before and after each condition, single-pulse transcranial magnetic stimulation will be delivered to the primary motor cortex to measure the amplitude of motor-evoked potentials and the duration of the resulting silent periods in the bicep brachii to quantify changes in corticospinal excitability and inhibition, respectively. Rapid maximal voluntary isometric contractions will be used to measure changes in rate of torque development, peak torque, and rate of muscle activation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
18
The intervention involved imagining, with no physical movement, of muscle contractions.
Kennesaw State University
Kennesaw, Georgia, United States
RECRUITINGChange in rate of torque development as measured by newton-meters per second
A measure of the capacity to increase muscle torque rapidly as determined by the slope of the torque-time curve
Time frame: Baseline, minute 20
Change in nervous system excitability as measured by electromyographic waveform aplitude following motor cortex stimulation
A measure of excitability for the corticospinal tract
Time frame: Baseline, minute 20
Change in isometric bicep strength as measured by newton-meters of torque
Isometric strength of a muscle
Time frame: Baseline, minute 20
Change in agonist muscle activation as measured by electromyography amplitude
A measure of the capacity at which the muscle is activated by the nervous system
Time frame: Baseline, minute 20
Change in antagonist co-activation as measured by electromyography amplitude
A measure of the capacity at which the antagonist muscle is activated by the nervous system
Time frame: Baseline, minute 20
Change in rate of agonist muscle activation as measured by electromyography amplitude
A measure of how quickly the nervous system activates the muscle
Time frame: Baseline, minute 20
Change in nervous system inhibition as measured by electromyographic waveform aplitude following motor cortex stimulation
A measure of inhibition for the corticospinal tract
Time frame: Baseline, minute 20
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