This clinical trial aims to determine whether BK329 reduces body fat in adults with overweight or obesity and to assess its safety. The main questions are: * Does BK329 reduce body fat in participants? * What side effects occur when participants take BK329?
Researchers will compare BK329 to a placebo to evaluate its effectiveness in reducing body fat. Participants will: * Take BK329 or a placebo daily for 12 weeks. * Visit the clinic every six weeks for checkups and tests.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Enrollment
100
Pusan National University Yangsan Hospital
Yangsan, South Korea
Total body fat (kg)
Using dual-energy X-ray absorptiometry at baseline and 12 weeks
Time frame: 12 weeks
Body fat percentage
Using dual-energy X-ray absorptiometry at baseline and 12 weeks
Time frame: 12 weeks
Lean body mass (kg)
Using dual-energy X-ray absorptiometry at baseline and 12 weeks
Time frame: 12 weeks
Body mass index (kg/m2)
Measured at baseline and 12 weeks
Time frame: 12 weeks
Body weight (kg)
Measured at baseline and 12 weeks
Time frame: 12 weeks
Waist-to-hip ratio
Measured at baseline and 12 weeks
Time frame: 12 weeks
Total cholesterol level (mg/dl)
Measured at baseline and 12 weeks
Time frame: 12 weeks
Triglycerides level (mg/dL)
Measured at baseline and 12 weeks
Time frame: 12 weeks
High-density lipoprotein cholesterol levels (mg/dL)
Measured at baseline and 12 weeks
Time frame: 12 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Low-density lipoprotein cholesterol levels (mg/dL)
Measured at baseline and 12 weeks
Time frame: 12 weeks
Free fatty acid level (mg/dL)
Measured at baseline and 12 weeks
Time frame: 12 weeks
High-sensitivity C-reactive protein (mg/dL)
Measured at baseline and 12 weeks
Time frame: 12 weeks
Total immunoglobulin E level (IU/mL)
Measured at baseline and 12 weeks
Time frame: 12 weeks
Neutrophil-to-lymphocyte ratio
Measured at baseline and 12 weeks
Time frame: 12 weeks