The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
1,100
Tablets for oral administration.
Placebo matched to SUZ for oral administration.
Capsules for oral administration.
Change From Baseline in the Weekly Average of Daily Pain Intensity on the Numeric Pain Rating Scale (NPRS) at Week 12 Compared to Placebo
Time frame: From Baseline up to Week 12
Change From Baseline in the Medical Outcomes Study 36-item Short-form Health Status (SF 36v2) Physical Component Summary (PCS) Score at Week 12 Compared to Placebo (pooled with data from Study VX24-548-111)
Time frame: From Baseline up to Week 12
Change From Baseline in the Weekly Average of Daily Pain Intensity on the NPRS at Week 12 Compared to Pregabalin
Time frame: From Baseline up to Week 12
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Placebo matched to Pregabalin for oral administration.
Pinnacle Research Group, LLC
Anniston, Alabama, United States
RECRUITINGSynexus Clinical Research - Birmingham
Birmingham, Alabama, United States
COMPLETEDAMR Daphne, AL
Daphne, Alabama, United States
COMPLETEDSynexus Clinical Research - Phoenix Central
Phoenix, Arizona, United States
COMPLETEDScottsdale Clinical Trials
Scottsdale, Arizona, United States
RECRUITINGNeuro-Pain Medical Center
Fresno, California, United States
RECRUITINGLong Beach Research Institute
Long Beach, California, United States
RECRUITINGAngel City Research, Inc
Los Angeles, California, United States
RECRUITINGEmpire Clinical Research
Pomona, California, United States
RECRUITINGClinical Trials Research
Sacramento, California, United States
RECRUITING...and 66 more locations