Assessment of Dimensional Changes Following Grafting With Microfragmented Adipose Tissue Loaded on Allograft on Ridge Preservation

N/ANot Yet RecruitingNCT06636461

Cairo University26 enrolled

Overview

Evaluation of maxillary alveolar ridge changes (bone quantity and quality as revealed by radiographic and Histomorphometry ) utilizing microfragmented adipose tissue loaded on allograft versus allograft only for maxillary posterior ridge preservation

All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on allograft will be utilized for the study group and allograft only for the control group. After 3-6 months, assessment of dimensional changes ( RG height \& width) on CBCT is performed and Histomorphometry will be evaluated via core biopsy at the time of implant placement in both groups. Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height and width from base line (1week) to 3-6 months postoperatively.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Hopeless Tooth

Interventions

microfragmented adipose tissue loaded on allograftPROCEDURE

microfragmented adipose tissue loaded on allograft on ridge preservation

Eligibility

Sex: ALLMin age: 21 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients requiring implant treatment after tooth extraction due to either unrestorable caries lesions or affected periodontium. Age group: above 18 years • Remaining natural teeth have good periodontal tissue support and occlusion showed sufficient inter arch space for future prosthesis. Exclusion Criteria: * • General contraindications to implant surgery. * Subjected to irradiation in the head and neck area less than 1 year before implantation. * Poor oral hygiene and motivation. * Severe bruxism or clenching. * Systemic, immunologic or debilitating diseases that could affect normal bone healing \& local pathosis. * Treated or under treatment of intravenous amino-bisphosphonates. * Active infection or severe inflammation in the area intended for implant placement. * Patients participating in other studies, if the present protocol could not be properly followed. * Heavy somkers

Locations (1)

Cairo Universty

Cairo, Giza Governorate, Egypt

Outcomes

Primary Outcomes

Alveolar ridge hight (bone quantity )

By CBCT

Time frame: Alveolar ridge hight (bone quantity ) by CBCT after 3-6 months

Secondary Outcomes

Alveolar ridge width.

By CBCT

Time frame: Alveolar ridge width. by CBCT after 3-6 months

Central Contacts

maha alnahdi, BDS

CONTACT

01145684357 maha.alnahdi@dentistry.cu.edu.eg

hesham elhawary, prof

CONTACT

01144446373 hesham.elhawary@dentistry.cu.edu.eg

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.