Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects

Tsvetalina Gerova-Vatsova48 enrolled

Overview

Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix derivatives in vertical bone defects Study of the effectiveness of the application of guided tissue regeneration in vertical bone defects with Barrier membrane and Barrier membrane and autogenous platelet-rich plasma

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Vertical Alveolar Bone Loss

Interventions

PRP( platelet rich plasma)PROCEDURE

regenerative therapy with PRP for vertical bone defects

EMD (Enamel Matrix Derivative)PROCEDURE

regenerative therapy with EMD for vertical bone defects

Guided Tissue Regeneration (barrier membrane)PROCEDURE

guided tissue regeneration with barrier membrane alone for vertical bone defects

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * good oral hygiene * written informed consent * age * no systemic diseases Exclusion Criteria: * smokers * horizontal bone loss * untreated periodontium disease

Locations (1)

Medical University - Varna

Varna, Varna, Bulgaria

Outcomes

Primary Outcomes

Probing depth in mm

Time frame: 6 months

Level of Margo Gingivalis in mm

Time frame: 6 months

Clinical attachment level in mm

Time frame: 6 months

The distance from the ECJ to the base of the bone defect in mm

Time frame: 6 months

The distance from the ECJ to the apex of the bone defect in mm

Time frame: 6 months

The width of the bone defect in mm

Time frame: 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.