Age-related Changes in Retinal Oxygen Extraction in Healthy Subjects

Inclusion Criteria: * Men and women aged between 18 and 80 years * Signed informed consent * Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant for the purpose of the study * Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant for the purpose of the study * Nonsmokers Exclusion Criteria: * Abuse of alcoholic beverages or drugs * Participation in a clinical trial in the 3 weeks preceding the study * Symptoms of a clinically relevant illness in the 3 weeks before the first study day * Blood donation during the previous 3 weeks * Pregnant or breast-feeding women