Oxygen Reserve Index in Different Fresh Gas Flow

Sakarya University64 enrolled

Overview

Our primary objective is to determine whether oxygen reserve index ORI can be a reliable and sensitive indicator of hypoxia and hyperoxia in low-flow anesthesia settings. Our secondary objective is to investigate the ORI changes during preoxygenation stage.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Oxygen Reserve Index

Interventions

Oxygen reserve indexDEVICE

Measuring oxygen reserve index during preoxygenation and under general anesthesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I-III patients * 18-75 years old * underwent general anesthesia * elective ear, nose and throat surgery, lasting longer than 60 minutes Exclusion Criteria: * who did not consent to participate, * those with finger deformities * unregulated diabetes mellitus, severe heart, kidney, or liver failure, sensitivities to local anesthetics or opioids, those who were morbidly obese (BMI \&gt;40 kg/m²), and breastfeeding women.

Locations (1)

Sakarya University Training and Research Hospital

Sakarya, Turkey (Türkiye)

Outcomes

Primary Outcomes

Oxygen Reserve Index Value

The Oxygen Reserve Index (ORI) is a real-time monitoring measure that captures the oxygen reserve status in the moderate hyperoxic range (PaO2 approximately 100 to 200 mmHg). ORI provides early warning of potential oxygenation disturbances before any changes occur in SpO2 and indicates the response to oxygen therapy. ORI ranges from 1 (high reserve) to 0 (no reserve) and measures changes in mixed venous oxygen saturation (SvO2) optically after arterial oxygen saturation reaches 100%.

Time frame: For each patient, from preoxygenation stage to the end of the general anesthesia

Data from ClinicalTrials.gov

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