The purpose of this study is to assess the safety of autologous Adipose-Derived Mesenchymal Stem Cell for use in End-Stage Liver Disease patients undergoing the creation of a duct-to-duct anastomosis during Living Donor Liver Transplantation.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Adipose derived autologous mesenchymal stromal cells; \[\~500,000 cells/cm2\] will be applied once to the biliary anastomosis using approximately 3-5 million cells in 5ml Lactated Ringer solution.
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Side effects
Number of subjects to experience systemic symptoms, irritation, inflammation, infections or biliary obstructions
Time frame: 24 months
Biliary complications
Number of subjects to develop biliary complications of strictures or leaks
Time frame: 24 months
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