This Study aims to evaluate the efficacy of opioid free general anesthesia in achieving enhanced recovery after surgery (ERAS) in laparoscopic bariatric surgery in terms of post-operative recovery time, cumulative pethidine consumption and number of episodes of postoperative nausea and vomiting(PONV).
While opioids have been commonly used in the operating room due to their effectiveness in pain management and anesthesia, there are numerous common side effects that have an impact on patient recovery. Obese patients or those with pre-existing respiratory difficulties such as sleep apnea or chronic obstructive pulmonary disease are more likely to experience respiratory failure after getting opiate therapy. Other effects of opioid use include gastro-intestinal obstacles such nausea, vomiting, and constipation. The concept of opioid-free anesthesia evolved due to the potential adverse side effects associated with intraoperative opioid usage. This study examines nociceptive monitoring's potential role in opioid-free anesthesia, as well as research on the topic. This study aims to compare the effects of an opioid-free anesthesia (OFA) regimen versus an opioid-based anesthesia (OBA) regimen on postoperative pain and enhanced recovery in patients undergoing bariatric surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
36
opioid based anesthesia analgesia will be offered by fentanyl in induction and maintenance according to Ideal Body Weight (IBW).
Analgesia will be offered by syringe containing ketamine and Dexmedetomidine in induction and maintenance according to IBW.
Time between the end of analgesic used and an Aldrete score > 9 (when applicable).
Decrease opioid usage ,decrease recovery time
Time frame: 15 minutes
Time between the end of operation to PACU
Decrease opioid usage ,decrease recovery time
Time frame: 15 minutes
Cumulative pethidine consumption
decrease the need to postoperative pethidine
Time frame: 24 hours postoperative
Number of episodes of nausea and vomiting [Time Frame: During the 24 hours following extubation].
number of episodes of nausea and vomiting postoperative
Time frame: 24 hours postoperative
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