The aim of this study is to investigate the effects of biopsychosocial status, quality of life, functional status and hematological markers on fatigue in individuals with SLE.
Study Type
OBSERVATIONAL
Enrollment
39
Pamukkale University
Denizli, Turkey (Türkiye)
Fatigue Assesment Scale
It is a scale consisting 10 items. The maximum score is 50. High score indicates high fatigue.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
FACIT Fatigue Scale
It is scale consisting 13 items. Scores range from 0-52. High score indicates low fatigue
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ)
It is a scale consist of 30 items. Scores range from 0-120. Higher scores indicate worse biopsychosocial status.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Short Form 36 (SF-36) Health Survey
The SF-36 consists of two dimensions, generating a profile of health-related quality of life.These dimensions are: physical health and mental health. Higher scores indicate better health.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
HEALTH ASSESSMENT QUESTIONNAIRE (HAQ)
The scale consists of 20 questions and includes 8 activities. The total score is obtained by summing the points earned from 8 activities and then dividing that sum by 8. Higher scores indicate worse functional status
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
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Routine blood test results
Participants' routine blood test results such as neutrophil (NEU (K/uL)) , monocyte (MONO (K/uL)), eosinophil (EO (K/uL)), leukocyte (WBC (K/uL)), lymphocyte (LYM (K/uL)), platelet (PLT (K/uL)) will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
Participants' routine blood test results such as calcium (Ca (mg/dL)), creatinine (mg/dL), c-reactive protein (CRP (mg/L)), uric acid (mg/dL) will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
The participants' rutin blood test such as aspartate aminotransferase (AST IU/L), alanine aminotransferase (ALT IU/L) will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Hematological indices
Neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), platelet/lymphocyte (PLR), platelet\*neutrophil/lymphocyte (systemic inflammatory index), monocyte/platelet (MTO), neutrophil\*monocyte/lymphocyte (systemic inflammatory response index), neutrophil\*monocyte\*platelet/lymphocyte (systemic inflammation aggregate index) obtained from complete blood counts will be calculated and recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
Procolcytonin (PCT (%)), erythrocyte distribution width (RDW (%)), platelet distribution width (PDW (%)) levels will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
Erythrocyte distribution width standard deviation (RDW-SD (fL)) will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
C3 complement (g/L) and C4 complement (g/L) levels will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
Blood urea nitrogen (BUN (mg/dL)) levels will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.
Routine Blood Test Results
Sedimentation (mm/h) will be recorded.
Time frame: Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period.