The Conus Brugada Syndrome Study

Barts & The London NHS Trust3 enrolled

Overview

An observational, analytical, cross sectional study investigating the effects of Conus branch and Right Ventricular (RV) Branch occlusion on surface ECG and intra-cardiac electrograms in patients undergoing percutaneous coronary intervention (PCI).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Brugada Syndrome

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Aged 18-85 * Patients able and willing to give their written informed consent. * Planned PCI of a CTO of a right coronary artery * Planned use of an anchor balloon in the Conus branch or RV branch Exclusion Criteria: * Patients considered unsuitable to participate by the research team (e.g., due to medical reasons, laboratory abnormalities, or subject's unwillingness to comply with all study related procedures). * Patients with a pre-existing, confirmed or possible diagnosis of Brugada Syndrome * Marked ST elevation or J point elevation on baseline (prior to procedure) ECG in the precordial leads (V1-V3) * Pregnancy. This will be tested by urine HcG measurement

Locations (1)

Barts Health NHS Trust

London, United Kingdom

Outcomes

Primary Outcomes

ECG and/or electrogram changes

Incidence of ECG changes resembling a Brugada type 1 pattern of coved ST elevation (one of the three Brugada types) specifically significant J point elevation in the precordial leads (V1-V3) and/or electrogram changes on the epicardial and/or endocardial intracardiac traces which will then be compared for differences and evidence of a transmural voltage gradient existing between them.

Time frame: During Procedure

Data from ClinicalTrials.gov

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