This study is a prospective, multicenter, phase II randomized controlled trial. We plan to screen 100 eligible thymoma patients for robotic-assisted thoracoscopic thymectomy (RATT) or video-assisted thoracoscopic thymectomy (VATT) at three medical centers in China. The trial was aimed to compare the perioperative outcomes between the two approaches.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Postoperative draingage volume
Postoperative draingage volume is the total draingage volume after surgery.
Time frame: Up to 7 days.
complete recestion rate
Time frame: Up to 7 days.
the counts of lymph node sampling
Time frame: From the time at start of the surgery to the time at end of the surgery. Up to 7 days.
operative time
Time frame: From the time at start of the surgery to the time at end of the surgery. Up to 7 days.
bleeding volume
Time frame: From the time at start of the surgery to the time at end of the surgery. Up to 7 days.
duration of drainage
Time frame: from the day of the surgery to the day of removal of drainage tubes. Up to 7 days.
postoperative hospital stays
Time frame: from the day of the surgery to the day of discharge. Up to 30 days
re-operation rate
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
C-reactive protein level at postoperaive day 1
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
C-reactive protein level at postoperaive day 2
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
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serum interleukin-6 level at postoperaive day 1
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
serum interleukin-6 level at postoperaive day 2
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
serum procalcitonin level at postoperaive day 1
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
serum procalcitonin level at postoperaive day 2
Time frame: from the day of the surgery to the day of discharge. Up to 7 days
pain visual analogue scale score at postoperative day 1, 2, 3 and 7
Time frame: from the day of the surgery to the postoperative day 7. Up to 7 days
quality of life score at postoperative day 30, 60 and 180
Time frame: from the day of the surgery to the postoperative day 180. Up to 180 days
complication rate
Time frame: from the day of the surgery to the day of discharge. Up to 30 days
3-year disease-free survival
Time frame: from the day of the surgery to the postoperative 3 years. Up to 3 years
3-year overall survival
Time frame: from the day of the surgery to the postoperative 3 years. Up to 3 years