Enabling Microbiomics- Driven Personalized Nutrition

N/AEnrolling By InvitationNCT06657001

Mayo Clinic4,001 enrolled

Overview

The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions. The main question investigators aim to answer is: Are host genetics, diet, and microbiome all important determinants of GI disorders, and how their relative contribution varies among individuals and populations.

Study Type

OBSERVATIONAL

Enrollment

4,001

Conditions

Inflammatory Bowel Disease (IBD)Irritable Bowel Syndrome (IBS)Celiac Disease Diarrhea Constipation Microbiome Crohn's Disease UC - Ulcerative Colitis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age greater than or equal to 18 years * Gastrointestinal patients with or without genomic sequencing results available for the following cohorts: * Inflammatory Bowel Disease (IBD) * Irritable Bowel Syndrome (IBS) * Crohn's Disease * Celiac Disease * Diarrhea * Constipation * Healthy age and sex matched controls with or without genomic sequencing results available o Control is defined as patients without gastrointestinal disease or no symptoms at time of sampling * Able to provide written, informed consent * Participant has a smartphone device with access to internet connection Exclusion Criteria: * Patients with cognitive impairment * Active use of antibiotics at the time of stool collection

Outcomes

Primary Outcomes

To Correlate Differences in Diet and Microbiome with Different GI Symptoms and Disease States

Investigators will prospectively follow the clinical course of the patients throughout the duration of the study. Patient health outcomes will be documented from their medical record while the study is actively enrolling or undergoing data analysis.

Time frame: From enrollment through study completion, an average of 1 year.

Data from ClinicalTrials.gov

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